Edward M Schwarz Selected Research

Collagen Type X

7/2006	Wnt induction of chondrocyte hypertrophy through the Runx2 transcription factor.
9/2005	Runx1/AML1/Cbfa2 mediates onset of mesenchymal cell differentiation toward chondrogenesis.
9/2004	Parathyroid hormone-related peptide (PTHrP) inhibits Runx2 expression through the PKA signaling pathway.
6/2002	Growth plate chondrocyte maturation is regulated by basal intracellular calcium.

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Edward M Schwarz Research Topics

Disease

33	Arthritis (Polyarthritis) 01/2021 - 05/2002
32	Infections 05/2022 - 08/2002
24	Osteolysis 01/2022 - 01/2002
23	Bone Resorption 01/2016 - 02/2002
19	Rheumatoid Arthritis 01/2022 - 05/2002
17	Osteomyelitis 01/2022 - 03/2010
17	Inflammation (Inflammations) 01/2021 - 03/2002
17	Neoplasms (Cancer) 07/2018 - 01/2002
8	Hypertrophy 10/2020 - 06/2002
8	Neoplasm Metastasis (Metastasis) 09/2015 - 04/2002
8	Osteoporosis 12/2014 - 12/2005
6	Synovitis 01/2020 - 01/2013
6	Osteoarthritis 01/2019 - 01/2002
5	Prostatic Neoplasms (Prostate Cancer) 02/2012 - 10/2002
4	Persistent Infection 01/2021 - 10/2018
3	Communicable Diseases (Infectious Diseases) 01/2021 - 09/2015
3	Interstitial Lung Diseases (Interstitial Lung Disease) 12/2019 - 01/2019
3	Wounds and Injuries (Trauma) 01/2019 - 03/2005
3	Reinfection 01/2019 - 01/2018
3	Cicatrix (Scar) 02/2015 - 06/2009
3	Psoriatic Arthritis 01/2014 - 01/2003
3	Breast Neoplasms (Breast Cancer) 02/2012 - 10/2002
2	Coinfection 10/2021 - 01/2021
2	Hypercalcemia (Milk Alkali Syndrome) 01/2020 - 01/2017
2	Diabetic Foot 01/2019 - 12/2018
2	Abscess 01/2018 - 01/2017
2	Fibrosis (Cirrhosis) 09/2017 - 03/2013
2	Obesity 01/2017 - 06/2015
2	Hypersensitivity (Allergy) 01/2017 - 01/2006
2	Arthralgia (Joint Pain) 01/2017 - 01/2016
2	Pain (Aches) 01/2016 - 01/2002
2	Renal Cell Carcinoma (Grawitz Tumor) 09/2015 - 02/2012
2	Tendon Injuries 02/2015 - 01/2012
2	Femoral Fractures (Femoral Fracture) 02/2013 - 04/2011
2	Intervertebral Disc Degeneration 08/2012 - 09/2011
2	Edema (Dropsy) 09/2010 - 07/2008
2	Metabolic Bone Diseases (Osteopenia) 12/2009 - 07/2003

Drug/Important Bio-Agent (IBA)

34	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2022 - 05/2002
16	Anti-Bacterial Agents (Antibiotics)IBA 05/2022 - 03/2015
13	CytokinesIBA 01/2021 - 03/2002
12	Pharmaceutical PreparationsIBA 01/2021 - 07/2003
12	Biomarkers (Surrogate Marker)IBA 10/2020 - 07/2008
9	Proteins (Proteins, Gene)FDA Link 07/2018 - 03/2002
8	RANK LigandIBA 01/2021 - 03/2002
8	OsteoprotegerinIBA 03/2010 - 03/2002
7	Biological ProductsIBA 10/2020 - 01/2008
5	Diphosphonates (Bisphosphonates)IBA 01/2022 - 10/2002
5	AntigensIBA 03/2021 - 11/2013
5	LigandsIBA 01/2021 - 03/2002
5	Hexosaminidases (Hexosaminidase)IBA 11/2020 - 04/2011
5	Immunoglobulin G (IgG)IBA 12/2018 - 04/2011
5	Monoclonal AntibodiesIBA 01/2018 - 04/2011
5	Transforming Growth Factor beta (TGF-beta)IBA 08/2010 - 05/2004
4	Vancomycin FDA LinkGeneric 01/2022 - 03/2015
4	Indocyanine Green (Cardio-Green)FDA LinkGeneric 01/2020 - 07/2010
4	Polymethyl Methacrylate (Sol)IBA 02/2019 - 08/2009
4	Anabolic AgentsIBA 09/2017 - 01/2008
4	Teriparatide (Parathar)FDA Link 03/2016 - 09/2008
4	Parathyroid Hormone (Parathormone)IBA 12/2014 - 09/2011
4	TitaniumIBA 10/2009 - 02/2002
4	NF-kappa B (NF-kB)IBA 06/2007 - 04/2005
4	Transcription Factors (Transcription Factor)IBA 07/2006 - 10/2003
4	Collagen Type XIBA 07/2006 - 06/2002
3	EnzymesIBA 01/2021 - 04/2005
3	VaccinesIBA 01/2021 - 10/2014
3	Bone Cements (Bone Glue)IBA 01/2021 - 10/2004
3	AntibodiesIBA 12/2019 - 12/2018
3	C-Reactive ProteinIBA 01/2019 - 11/2013
3	ultra-high molecular weight polyethylene (UHMWPE)IBA 01/2016 - 09/2002
3	Messenger RNA (mRNA)IBA 09/2015 - 09/2004
3	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 02/2015 - 05/2008
3	Matrix Metalloproteinases (MMPs)IBA 02/2015 - 06/2009
3	GlucocorticoidsIBA 11/2012 - 11/2003
3	Alendronate (Alendronate Sodium)FDA LinkGeneric 03/2010 - 10/2003
3	ChemokinesIBA 01/2010 - 12/2005
3	Dinoprostone (PGE2)FDA Link 10/2009 - 01/2002
3	Receptor Activator of Nuclear Factor-kappa B (TRANCE-R)IBA 06/2007 - 02/2002
2	sitafloxacinIBA 01/2022 - 02/2019
2	Anti-Infective Agents (Microbicides)IBA 01/2021 - 10/2018
2	Rifampin (Rifampicin)FDA LinkGeneric 02/2019 - 01/2017
2	Gentamicins (Gentamicin)FDA LinkGeneric 02/2019 - 03/2010
2	MetalsIBA 01/2017 - 01/2006
2	AntioxidantsIBA 01/2016 - 05/2013
2	Tumor Necrosis Factor InhibitorsIBA 08/2015 - 11/2003
2	Vascular Endothelial Growth Factor CIBA 08/2011 - 05/2008
2	Caspase 3 (Caspase-3)IBA 04/2011 - 04/2005
2	DNA (Deoxyribonucleic Acid)IBA 04/2010 - 06/2002
2	Etanercept (Enbrel)FDA Link 03/2010 - 11/2003

Therapy/Procedure

40	Therapeutics 01/2021 - 08/2003
6	Arthroplasty 01/2017 - 02/2002
5	Debridement 05/2022 - 03/2015
4	Surgical Amputation (Amputations) 03/2021 - 01/2019
4	Replacement Arthroplasty 09/2015 - 05/2002
4	Prostheses and Implants (Prosthesis) 12/2014 - 01/2002
4	Drug Therapy (Chemotherapy) 04/2011 - 08/2002
3	Immunotherapy 01/2021 - 01/2018
3	Reoperation 01/2018 - 04/2011
2	Salvage Therapy 01/2019 - 12/2018
2	Orthopedic Procedures 01/2019 - 01/2019
2	Hip Replacement Arthroplasty (Total Hip Replacement) 01/2016 - 11/2003